Bui Van Dat, PharmD
Vinmec Research Institute of Stem Cell and Gene Technology
Research scientist
Biography
Dr. Bui Van Dat is a pharmacist-scientist specializing in extracellular vesicle (EV)-based therapeutics and advanced drug delivery systems. He received his combined M.S.–Ph.D. degree in Chemical Engineering from Sungkyunkwan University (South Korea), where he was supervised by Prof. Jae Hyung Park. His doctoral research focused on polysaccharide-based engineering strategies to enhance the stability, targeting, and therapeutic efficacy of stem cell-derived extracellular vesicles.
Dr. Bui is currently a researcher at the Vinmec Research Institute of Stem Cell and Gene Technology, College of Health Sciences, VinUniversity, Vietnam. His work integrates pharmaceutical sciences, biomaterials, and nanomedicine to develop translational EV-based products for regenerative medicine, immune modulation, metabolic diseases, and cancer therapy.
• Engineering and functionalization of extracellular vesicles (EVs) from stem cells, yeasts, probiotics, and tumors
• Polysaccharide-based modification of EVs for enhanced stability, targeting, and biological function
• EV-based drug delivery systems (hydrogel, microneedles, lyophilized formulations)
• EV-mediated immunomodulation and cancer vaccine development
• Therapeutic applications of EVs in wound healing, autoimmune diseases, metabolic disorders, and cancer
• Pharmaceutics and advanced drug delivery systems
• Nanomedicine and biomaterials in biomedical applications
• Translational pharmaceutical research and formulation development
• Experimental design and data analysis in biomedical sciences
• Van Dat Bui, et al. Dissolving microneedles for long-term storage and transdermal delivery of extracellular vesicles. Biomaterials, 2022.
• Van Dat Bui, et al. Chondroitin sulfate-based microneedles for transdermal delivery of stem cell-derived extracellular vesicles to treat rheumatoid arthritis. Journal of Controlled Release, 2024.
• Han KH, Van Dat Bui, et al. Immunogenic extracellular vesicles derived from ER-stressed tumor cells as cancer vaccines. ACS Nano, 2024.
• Park JY, Van Dat Bui, et al. Stem cell-derived extracellular vesicles in skin anti-aging treatments. ACS Nano, 2025.
• Ph.D. (Combined M.S.–Ph.D.) in Chemical Engineering, Sungkyunkwan University, South Korea (09.2019–02.2025). Thesis: Polysaccharide-Based Engineering for Applications of Stem Cell-Derived Extracellular Vesicles
• Degree of Pharmacist, Hanoi University of Pharmacy, Vietnam (09.2014–08.2019)
• Korean Society of Biomaterials – Excellence Award (Poster), 2023
• Korean Society of Molecular Imaging – Excellence Award (Oral Presentation), 2023
• Brain Korea (BK21) Excellence Graduate Student Award, 2022 & 2023
• Vietnam–Japan Scientific Exchange Meeting – Excellence Poster Award, 2018